Adaptive coherence volume in full-field optical coherence tomography

نویسندگان

چکیده

Optical sectioning is instrumental for the observation of extended biological samples. It allows only a slice sample while rejecting contributions from out focus depths. The acquisition whole volume then requires an axial displacement or focus. To satisfy Nyquist sampling, this has to be equal half resolution. As lateral and resolutions are coupled by numerical aperture microscope objective in most imaging techniques, high-resolution time-consuming task, especially caused slow scanning. Here, we propose adapt resolution, extent coherence volume, filtering spectrum illumination interferometric technique. We applied our approach on full-field optical tomography show tuning 1.5 15 μ m, allowing both time amount data. finally demonstrate that method suited image large samples such as millimetric engineered tissues.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Polarization-sensitive full-field optical coherence tomography.

We present a polarization-sensitive full-field optical coherence tomography system that can produce high-resolution images of the linear retardance and reflectivity properties of biological media. En face images can be delivered at a frame rate of 3.5 Hz by combination of interferometric images acquired by two CCD cameras in an interference microscope illuminated with a tungsten halogen lamp. I...

متن کامل

Thermal-light full-field optical coherence tomography.

We have built a high-resolution optical coherence tomography (OCT) system, based on a Linnik-type interference microscope, illuminated by a white-light thermal lamp. The extremely short coherence length of the illumination source and the large aperture of the objectives permit resolution close to 1 microm in three dimensions. A parallel detection scheme with a CCD camera provides cross-section ...

متن کامل

Large Field, High Resolution Full-Field Optical Coherence Tomography

We present a benchmark pilot study in which high-resolution Full-Field Optical Coherence Tomography (FF-OCT) was used to image human breast tissue and is evaluated to assess its ability to aid the pathologist's management of intra-operative diagnoses. FF-OCT imaging safety was investigated and agreement between FF-OCT and routinely prepared histopathological images was evaluated. The compact se...

متن کامل

Cross Talk in Full-Field Optical Coherence Tomography

The formation of cross-sectional images of biological tissues requires the discrimination between light conveying useful information—that is, propagating directly from object to image— from the abundant parasitic light caused by multiple scattering inherent to turbid media [1, 2]. In optical coherence tomography (OCT) [3], selective detection of light undergoing a single backscatter event (refl...

متن کامل

Motion artifact suppression in full-field optical coherence tomography.

Significant motion artifacts limit the performance of conventional full-field optical coherence tomography (FF-OCT) for in-vivo imaging. We present a theoretical and experimental study of those limitations. A new FF-OCT system suppressing most of artifacts due to sample motions is demonstrated using instantaneous phase shifting with nonpolarizing optics and pulsed illumination. The experimental...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: OSA continuum

سال: 2021

ISSN: ['2578-7519']

DOI: https://doi.org/10.1364/osac.442310